A normal, average guy who lives in New York City becomes dependent on an evil, disembodied brain. The brain feeds the guy a narcotic substance in exchange for his unwilling assistance in obtaining the brains of innocent victims for sustenance. This turns into a tour of circa-1980s underground NYC clubs, backlots, and other seedy locations. One scene features the band Swimming Pool Cues playing the song "Corruption."

David Kirmani,a medical professional, lives in an apartment with his sweetheart, Erica Bain, a radio host, and his dog. They usually take the dog out for a stroll in nearby Central Park and let him run and fetch. One day while at the park they let the dog run without a leash, and when he does not return or respond to their calls, they frantically search for him. They eventually find him being held by three men who want a reward. When David refuses, they start to molest Erica and David intervenes. Two of the men assault the couple, while the third uses a camcorder to film this incident. Erica is knocked unconscious, and regains her senses several days later in a hospital. She is told the shocking news that David was killed and the dog is missing. A traumatized Erica returns home to try and regain her life. She also visits the police station but does not get much help. Fearful of a repeat of this type of incident...